At the age of 20, he moved to Chennai and tried to make a breakthrough into the film industry, but was hindered by his lack of contacts and instead worked for a private company for nine years. He also had an interest in lyric writing, often writing lyrics for parody versions of popular songs, while becoming trained in various instruments including the harmonium and guitar.
He earned pocket money during his school days by writing love letters for his classmates. His father was a poet and a fiction writer and his mother was a housewife, while Ramaiah was their eldest child. Thambi Ramaiah was born in Rarapuram village in Pudukkottai, and initially entered the film industry hoping to become a screenwriter. He directed three films, Manu Needhi (2000), Indiralohathil Na Azhagappan (2008) and Maniyaar Kudumbam (2018).
He has also worked occasionally as a lyricist. Thambi Ramaiah is an Indian actor, director and comedian who works in the Tamil film industry.